One Health

Antibiotic use (ABU) in animals is postulated to be a major contributor to selection of antibiotic resistance (ABR) which subsequently causes infections in human populations. However, there are few quantifications of the size of this association. Denmark, as a country with high levels of pig production and good surveillance data, is an ideal case study for exploring this association. In this paper, we compile a dataset on ABU across several animal species and antibiotic classes, and data on the...

ObjectiveSignificant opportunities for understanding the co-occurrence of conditions across species in coincident households remain untapped. We determined the feasibility of creating a Companion Care Registry (CCR) for analysis of health data from the University of Colorado Health (UCHealth) patients and their companion animals who received veterinary care at the geographically-adjacent Colorado State University Veterinary Teaching Hospital (CSU-VTH). Materials and MethodsUsing a hybrid determ...

IntroductionEmerging and/or reemerging infectious diseases (EIDs) in the East Africa region are associated with climate change induced environmental drivers. There is a need for a comprehensive understanding of these environmental drivers and to adopt an integrated risk analysis (IRA) framework for addressing a combination of the biological, environmental, and socio-economic factors that increases population vulnerabilities to EID risks, to inform biological risk mitigation and cross-sectoral de...

The One Health framework highlights the interconnectedness of human, animal, and environmental health, requiring interdisciplinary and multisectoral collaboration to address complex global health challenges. This scoping review will systematically map how studies and policy initiatives have incorporated socioecological interconnections within the One Health paradigm (2004 to 2025), following Joanna Briggs Institute guidance and the PRISMA Sc checklist. Searches will be conducted in PubMed, Scopu...

Compassion fatigue is a well-documented hazard among healthcare and veterinary professionals, yet the psychological toll on informal caregivers of feral cat colonies, likely numbering several tens of thousands in Portugal, remains largely unexplored. This cross-sectional study examines internal and external factors associated with the secondary traumatic stress component of compassion fatigue among 172 informal caregivers in Portugal. Secondary traumatic stress refers to work-related secondary e...

Current published guidance on how to evaluate antibiotic resistance (ABR) from a One Health perspective has focussed on the evaluation of intervention design and of the intervention implementation process. For efficient resource allocation, it is also important to consider quantitative measures of intervention impact. In particular, there has been little discussion of how to practically evaluate ABR-related agri- and aquaculture interventions from a public health perspective. Lessons can be lear...

International organizations are calling for One Health approaches to tackle antibiotic resistance (ABR). In France, the diversity of surveillance programmes makes it difficult to get an overview of the current surveillance system and its level of integration. This study aimed to map and characterise all French surveillance programmes for ABR, antibiotic use (ABU) and antibiotic residues in humans, animals, food and the environment, to identify integration points, gaps and overlaps. A literature...

Antibiotic resistance (ABR) is a severe global public health threat, particularly in low- and middle-income countries (LICs and LMICs), where socio-economic and infrastructural factors impede effective ABR management. Here, we identify critical challenges, including disparity in the volume of research related to ABR stewardship for the dairy industry, that hinder the success of national action plans in LICs and LMICs. We conducted a literature review to pinpoint specific challenges to ABR stewar...

The One Health conceptual framework envisions human, animal, and environmental health as interconnected. This framework has achieved remarkable progress in the control of zoonotic diseases, but it commonly neglects the environmental domain, implicitly prioritizes human life over the life of other beings, and fails to consider the political, cultural, social, historical, and economic contexts that shape the health of multispecies collectives. We have developed a novel theoretical framework, Relat...

Antimicrobial resistance (AMR) represents a growing global public health threat, undermining therapeutic efficacy and disproportionately affecting vulnerable populations. In Ecuador, the situation is exacerbated by weak surveillance systems and fragmentation among the human, animal, and environmental health sectors. This study analyzes current national approaches that address AMR in Ecuador from a One Health (OH) perspective, with an emphasis on governance, public policy, health infrastructure, ...

TitleSpatial analysis of methicillin-resistant Staphylococcus aureus carriage (MRSA) screening yield at hospital admission in a livestock-dense region PurposeIn the Netherlands, patients with a risk factor for methicillin-resistant Staphylococcus aureus (MRSA) carriage, such as foreign hospital stay and contact with livestock (pigs, veal calves and/or broilers) are actively screened upon hospital admission. This study aimed to give insight in the geographical clustering patterns of MRSA carriag...

ObjectivesTo estimate daily transmission rates of ESBL-producing Enterobacterales across hospital environment surface, animal, and community environmental settings in Singapore to address scarce empirical data that constrains One Health modelling and policy design. MethodsA structured expert elicitation was conducted with a panel of eight experts: three for the clinical sector, three for the environmental sector, and two for the animal sector. Expert judgments were aggregated using both equal-w...

BackgroundAntimicrobial resistance (AMR) is a complex global health threat with uneven impacts across regions. In Australia, the AMR burden varies geographically, with up to 50% of infections now resistant to antibiotics in northern Australia. MethodsThis qualitative study engaged stakeholders across One Health sectors in the Northern Territory to explore perspectives on AMR. Thematic analysis of interview data informed the development of a causal loop diagram, grounded in systems thinking, to ...

IntroductionOccupational injuries are prevalent within the veterinary sector, though their true extent is unknown as evidence indicates widespread under-reporting of injuries. This study aimed to: assess injury under-reporting across roles in UK veterinary practices; and audit the type, frequency, and outcomes of workplace injuries within a large veterinary organisation. MethodsA retrospective audit was conducted on a large veterinary organisations accident reporting system in 2022. Under-repor...

BackgroundEnvironmental and Regulatory (ER) services, provided by local authorities, play a key role in public health protection. Food safety teams within ER services carry out regular food hygiene inspections, advice and education visits, and investigate foodborne disease outbreaks. Following the 2008 financial crisis, local authorities have faced substantial funding cuts. This study investigates the impact of local government expenditure reductions on food safety services. MethodsWe used fixe...

Antibiotic resistance (ABR), the capacity of bacterial pathogens to survive in the presence of antibiotics, is an increasingly pressing issue for human health worldwide. The use of antibiotics (ABU) in humans and livestock animals, is considered the main driver of the global increase in ABR prevalence, but the shape and size of this relationship at the population level is still uncertain. In the UK, the bacterial pathogen Campylobacter is a major cause of foodborne infection, with most infectio...

The benefits of animal-assisted interventions (AAI), to utilize companion animals as an adjunctive treatment modality, is well-established and a burgeoning research field. However, few studies have evaluated the potential hazards of these programs, such as the potential for therapy animals to transfer hospital-associated pathogens between individuals and the hospital environment. Here we review the current literature on the possible risks of hospital-based AAI programs, including zoonotic pathog...

Antimicrobial resistance (AMR) surveillance systems involve multiple stakeholders and multilevel standard operating procedures, which increase in complexity with further integration of the One Health (OH) concept. AMR is a OH challenge. It is crucial for the success of an AMR surveillance system to evaluate its performance in meeting the proposed objectives, while complying with resource restrictions. The OH-EpiCap tool was created to evaluate the degree of compliance of hazard surveillance acti...

Sporotrichosis is an emerging zoonosis with growing impact in Brazils urban areas, aggravated by the absence of effective public health policies and standardized surveillance protocols, especially for free-roaming cats. This study evaluated the implementation of a surveillance and control protocol for sporotrichosis in an urban area with high densities of community cats and frequent abandonment, including animals testing positive for the disease. A retrospective, descriptive, observational epide...

ObjectivesThis study aimed to describe the incidence, demographics, and context of livestock-related deaths 2010-2023. Study designA descriptive analysis of the Health and Safety Executives Fatal injuries in agriculture, forestry and fishing in Great Britain annual reports. MethodsAnnual incidence of death was calculated. Demographic and contextual information were extracted, and data stratified by whether the victim was a farmer or member of the public. Statistical comparisons were made usin...